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Oxycodone powder is a semisynthetic opioid synthesized from thebaine, an opioid alkaloid found in the Persian poppy, and one of the many alkaloids found in the opium poppy. It is a controlled substance in the United States with a DEA Schedule II classification due to its high potential for abuse and addiction. Oxycodone powder has been used for many years to treat moderate to severe pain, often in combination with other medications such as acetaminophen or ibuprofen.